EducationJuly 4, 2026作者:Testsubstances3,080 reads

Complete Guide to Reagent Test Kits: How They Work and Which Ones You Need

A comprehensive breakdown of every major reagent — Marquis, Ehrlich, Mecke, Morris, Froehde, and more — what each detects, and how to build your testing toolkit.

What Are Reagent Test Kits?

Reagent test kits contain chemical solutions that produce characteristic color changes when they contact specific compounds. Think of them as chemical fingerprinting — each substance leaves a unique color signature when exposed to different reagents. By running multiple reagents, you build a "color profile" that identifies the substance.

These tests are:

  • Qualitative — they identify what a substance IS, not how much
  • Presumptive — they strongly indicate but cannot 100% prove identity
  • Destructive — the sample is consumed during testing (you only need 2-5mg)

The Major Reagents: A Complete Reference

Marquis Reagent

Detects: MDMA, MDA, amphetamine, methamphetamine, opiates, 2C-B, DXM

Color with MDMA: Deep purple/black (instant)

Use case: The most versatile single reagent. Every testing kit should include Marquis. It's the first-line test for stimulants and MDxx compounds. Get Marquis →

Ehrlich Reagent

Detects: LSD, DMT, psilocybin, psilocin, 5-MeO-DMT, other indoles

Color with LSD: Purple/pink (develops over 1-5 minutes)

Use case: Essential for psychedelic testing. Ehrlich specifically reacts with the indole ring structure. A negative Ehrlich on a tab sold as LSD is a major red flag for NBOMe compounds. Get Ehrlich →

Mecke Reagent

Detects: MDMA, heroin, morphine, codeine, oxycodone

Color with MDMA: Green to dark blue/black

Use case: Excellent secondary confirmation for MDMA and critical for opioid identification. Mecke produces distinctly different colors for different opioids. Get Mecke →

Morris Reagent

Detects: Ketamine, 2F-DCK, DCK, other arylcyclohexylamines

Color with Ketamine: Deep purple/blue (instant)

Use case: The gold standard for ketamine testing. Morris was specifically developed to detect ketamine and distinguish it from other dissociatives. Get Morris →

Simon's Reagent (Two-Part)

Detects: Secondary amines — MDMA vs MDA, methamphetamine vs amphetamine

Color with MDMA/meth: Bright blue

Color with MDA/amphetamine: No reaction

Use case: The only reagent that reliably distinguishes primary from secondary amines. Without Simon's, you can't tell MDMA from MDA. Get Simon's →

Froehde Reagent

Detects: MDMA, synthetic cathinones, synthetic opioids, aspirin

Color with MDMA: Greenish-black to blue-black

Use case: Excellent for detecting cathinone adulterants that Marquis might miss. Also useful for distinguishing MDMA variants. Get Froehde →

Hofmann Reagent

Detects: LSD, other lysergamides

Color with LSD: Blue/purple (slow — develops over 5-30 minutes)

Use case: Slower but more specific than Ehrlich for LSD. Used as secondary confirmation in comprehensive psychedelic testing. Get Hofmann →

Liebermann Reagent

Detects: Broad-spectrum — cocaine, MDMA, aspirin, paracetamol, sugar alcohols

Color: Varies widely by compound

Use case: Excellent first-line broad screening tool. Produces distinctive colors for many common adulterants and cutting agents. Get Liebermann →

Mandelin Reagent

Detects: Ketamine, cocaine, PMA, methamphetamine

Color with Ketamine: Deep orange/red

Use case: Secondary confirmation for ketamine. Also detects PMA/PMMA which can be missed by other reagents. Get Mandelin →

Folin Reagent

Detects: Piperazines (BZP, TFMPP, mCPP)

Color: Varies by piperazine compound

Use case: Specialized for detecting piperazines sold as MDMA or amphetamine substitutes. Important for comprehensive testing. Get Folin →

How Many Reagents Do You Need?

Testing GoalMinimum ReagentsOur Recommendation
MDMA/Ecstasy only3 (Marquis, Simon's, Froehde)MDMA Complete Kit
General stimulants3 (Marquis, Simon's, Liebermann)3-in-1 Starter Kit
Psychedelics2 (Ehrlich, Hofmann)LSD Complete Kit
Ketamine2 (Morris, Mandelin)Ketamine Test Kit
Comprehensive6+Pro 6-in-1 Kit
Complete coverage9Complete 9-Reagent Kit

Storage and Shelf Life

Reagent bottles stored properly in a cool, dark place (refrigerator is ideal) last 12-18 months. Signs of expiration: darkened liquid in the bottle, weak or muddy reactions, failure to produce expected color on known substances.

Testing saves lives. No single test is perfect — always use multiple reagents and follow dosing safety practices.

Further reading: Reagent storage guide | Best test kit bundles | How to choose a kit*

reagent testingMarquisEhrlichharm reductionbeginners guide

Kits Mentioned in This Article

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