Emergency Guides
What to do when something goes wrong. Recognition, immediate response, and when to call for help. These are first-aid references, not medical advice.
Emergency Numbers
US/CA: 911 · UK: 999 · AU: 000 · EU: 112
Opioid Overdose: What to Do Right Now
Fentanyl, heroin, nitazenes, oxycodone — recognition and immediate response
Stimulant Overdose: Cocaine, Meth, and Amphetamine
Overheating, cardiac distress, seizures — recognition and cooling
Serotonin Syndrome: MDMA, Antidepressants, and the Overheating Emergency
When too much serotonin becomes life-threatening
Drug-Induced Psychotic Episode: What to Do When Someone Breaks from Reality
LSD, psilocybin, stimulants, and cannabis — de-escalation and safety
GHB/GBL Overdose: Unconsciousness, Airway, and Why Minutes Matter
The dose-response curve is steep. One milliliter too much and the person is unconscious.
Heat Stroke at Festivals: MDMA, Dancing, and When Cooling Becomes Critical
Hyperthermia is a leading cause of drug-related death at music events
Polydrug Emergencies: When Mixing Substances Goes Wrong
Alcohol + opioids, MDMA + antidepressants, stimulants + depressants — the dangerous combinations and what to do
DISCLAIMER: These guides provide first-aid guidance for drug-related emergencies. They are not a substitute for professional medical advice, diagnosis, or treatment. Always call emergency services in a life-threatening situation. Information compiled from public health sources including SAMHSA, EMCDDA, and recognized harm reduction organizations. TestSubstances.com is not responsible for any actions taken based on this information.